There's a lot you can do to lift the blues, but when it comes toserious depression, you're going to need an expert's help. Men withdepression are twice as likely to commit suicide as their femalecounterparts. See your physician if you're experiencing several ofthe following: Feeling down or low most of each day Losing interestin almost all activities Experiencing significant weight gain or lossInability to sleep Feeling agitated Feeling fatigued Experiencinginappropriate guilt or feelings of worthlessness Inability toconcentrate or make decisions Having suicidal thoughts

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